Evolution of Molecular Circuitries

Enard Lab

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Research

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Selected Publications

Edenhofer, F. C., Térmeg, A., Ohnuki, M., Jocher, J., Kliesmete, Z., Briem, E., Hellmann, I., & Enard, W. (2024). Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi. iScience, 27(6), 110090. https://doi.org/10.1016/j.isci.2024.110090

Jocher, J., Edenhofer, F. C., Müller, S., Janssen, P., Briem, E., Geuder, J., & Enard, W. (2024). Generation and characterization of two Vervet monkey induced pluripotent stem cell lines derived from fibroblasts. Stem cell research, 75, 103315. https://doi.org/10.1016/j.scr.2024.103315

Jocher, J., Edenhofer, F. C., Müller, S., Janssen, P., Briem, E., Geuder, J., & Enard, W. (2024). Generation and characterization of two fibroblast-derived Baboon induced pluripotent stem cell lines. Stem cell research, 75, 103316. https://doi.org/10.1016/j.scr.2024.103316

Jocher, J., Edenhofer, F. C., Janssen, P., Müller, S., Lopez-Parra, D. C., Geuder, J., & Enard, W. (2024). Generation and characterization of three fibroblast-derived Rhesus Macaque induced pluripotent stem cell lines. Stem cell research, 74, 103277. https://doi.org/10.1016/j.scr.2023.103277

Kliesmete, Z., Wange, L. E., Vieth, B., Esgleas, M., Radmer, J., Hülsmann, M., Geuder, J., Richter, D., Ohnuki, M., Götz, M., Hellmann, I., & Enard, W. (2023). Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals. eLife, 12, e83593. https://doi.org/10.7554/eLife.83593

Janjic, A., Wange, L. E., Bagnoli, J. W., Geuder, J., Nguyen, P., Richter, D., Vieth, B., Vick, B., Jeremias, I., Ziegenhain, C., Hellmann, I., & Enard, W. (2022). Prime-seq, efficient and powerful bulk RNA sequencing. Genome biology, 23(1), 88. https://doi.org/10.1186/s13059-022-02660-8

Geuder, J., Wange, L. E., Janjic, A., Radmer, J., Janssen, P., Bagnoli, J. W., Müller, S., Kaul, A., Ohnuki, M., & Enard, W. (2021). A non-invasive method to generate induced pluripotent stem cells from primate urine. Scientific reports, 11(1), 3516. https://doi.org/10.1038/s41598-021-82883-0

Bagnoli, J. W., Wange, L. E., Janjic, A., & Enard, W. (2019). Studying Cancer Heterogeneity by Single-Cell RNA Sequencing. Methods in molecular biology (Clifton, N.J.), 1956, 305–319. https://doi.org/10.1007/978-1-4939-9151-8_14

Bagnoli, J. W., Ziegenhain, C., Janjic, A., Wange, L. E., Vieth, B., Parekh, S., Geuder, J., Hellmann, I., & Enard, W. (2018). Sensitive and powerful single-cell RNA sequencing using mcSCRB-seq. Nature communications, 9(1), 2937. https://doi.org/10.1038/s41467-018-05347-6

Ziegenhain, C., Vieth, B., Parekh, S., Hellmann, I., & Enard, W. (2018). Quantitative single-cell transcriptomics. Briefings in functional genomics, 17(4), 220–232. https://doi.org/10.1093/bfgp/ely009

Ziegenhain, C., Vieth, B., Parekh, S., Reinius, B., Guillaumet-Adkins, A., Smets, M., Leonhardt, H., Heyn, H., Hellmann, I., & Enard, W. (2017). Comparative Analysis of Single-Cell RNA Sequencing Methods. Molecular cell, 65(4), 631–643.e4. https://doi.org/10.1016/j.molcel.2017.01.023

Enard W. (2016). The Molecular Basis of Human Brain Evolution. Current biology : CB, 26(20), R1109–R1117. https://doi.org/10.1016/j.cub.2016.09.030

Hammerschmidt, K., Schreiweis, C., Minge, C., Pääbo, S., Fischer, J., & Enard, W. (2015). A humanized version of Foxp2 does not affect ultrasonic vocalization in adult mice. Genes, brain, and behavior, 14(8), 583–590. https://doi.org/10.1111/gbb.12237

Enard W. (2015). Human evolution: enhancing the brain. Current biology : CB, 25(10), R421–R423. https://doi.org/10.1016/j.cub.2015.03.031

Enard W. (2014). Mouse models of human evolution. Current opinion in genetics & development, 29, 75–80. https://doi.org/10.1016/j.gde.2014.08.008

Enard W. (2014). Comparative genomics of brain size evolution. Frontiers in human neuroscience, 8, 345. https://doi.org/10.3389/fnhum.2014.00345

Wunderlich, S., Kircher, M., Vieth, B., Haase, A., Merkert, S., Beier, J., Göhring, G., Glage, S., Schambach, A., Curnow, E. C., Pääbo, S., Martin, U., & Enard, W. (2014). Primate iPS cells as tools for evolutionary analyses. Stem cell research, 12(3), 622–629. https://doi.org/10.1016/j.scr.2014.02.001